[Drug-induced readjustment of therapy-resistant hypertension]

By a combined vasodilator-[diisopropylamine (disostat), dihydralazine (depressan)] furosemide- (furesis-) infusion therapy was tried to achieve a new stabilisation of the blood pressure of therapy-refractory patients with hypertension. Propranolol (Obsidan) was additionally administered for the suppression of a sympathetic counter-regulation. On 3 patients is demonstrated how by a ten days' intensive decrease of the blood pressure and decrease of the extracellular fluid volume the therapy resistance may be interrupted and a repeated response to an oral antihypertensive standard therapy may be achieved.