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[Dermatological incompatibility reaction to X5Cr-Ni-Mo 18.10 steel implants in animal experiments]
Zeitschrift Fur Experimentelle Chirurgie
|January 1, 1978
Abstract:
Metal allergy is surveyed in detail. Especially the development of eczema by means of metallic implantates containing chromium or nickel. The results from two series of experiments on guinea-pigs are presented. The first series proves that after preceding sensibilization by potassium bichromate or nickel-II-sulfate eczemas may be induced in the guinea-pig by X 5 Cr Ni Mo 18.10 steel implantates. Positive skin reactions in the patch test prove the possibility of sensibilization by X 5 Cr Ni Mo 18.10 steel in a second series of animals preoperatively negative.