Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Cimetidine premedication in elective caesarean section

B G Pickering, R J Palahniuk, M Cumming

    Canadian Anaesthetists' Society Journal
    |January 1, 1980
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Do rural primary health care nurses feel equipped for palliative care?

    Australian journal of primary health·2012
    Same author

    In praise of the annual check-up.

    Canadian family physician Medecin de famille canadien·2011
    Same author

    [Not Available].

    Canadian family physician Medecin de famille canadien·2011
    Same author

    A filing system for medical literature.

    Canadian family physician Medecin de famille canadien·2011
    Same author

    Removal of C-spine protection by A&E triage nurses: a prospective trial of a clinical decision making instrument.

    Emergency medicine journal : EMJ·2006
    Same author

    Antiangiogenic potential of camptothecin and topotecan.

    Cancer chemotherapy and pharmacology·1999

    Cimetidine injections and oral antacids both raise gastric pH in pregnant patients but neither fully prevents high gastric volumes. Preventative measures are still needed during anesthesia induction for Caesarean sections.

    Area of Science:

    • Obstetrics and Gynecology
    • Anesthesiology
    • Pharmacology

    Background:

    • Pregnant patients undergoing Caesarean sections are at risk of aspiration due to high gastric volumes.
    • Preventative measures are crucial during anesthesia induction to mitigate aspiration risks.

    Purpose of the Study:

    • To compare the efficacy of intramuscular Cimetidine versus oral antacid premedication in reducing gastric volume and increasing gastric pH.
    • To evaluate the reliability of these methods in preventing aspiration during elective Caesarean sections.

    Main Methods:

    • A study involving 17 patients undergoing elective Caesarean section.
    • Comparison of a single intramuscular injection of Cimetidine with oral antacid premedication.
    • Measurement of gastric volume and pH after anesthesia induction.

    Related Experiment Videos

    Main Results:

    • Both Cimetidine and antacid increased gastric pH, but neither was completely reliable.
    • Seven patients in the Cimetidine group and four in the antacid group had gastric volumes > 50 ml.
    • Two patients in each group had gastric pH < 2.5 post-induction.

    Conclusions:

    • Intramuscular Cimetidine is comparable to oral antacids in raising gastric pH.
    • Neither Cimetidine nor antacids reliably reduce gastric volumes to safe levels in all pregnant patients.
    • The need for preventative measures against aspiration during anesthesia induction in pregnant patients is reconfirmed.