Related Experiment Video

Updated: Jan 10, 2026

Author Spotlight: Development and Challenges of Feeding Assays for Insect Pest Management
04:51

Author Spotlight: Development and Challenges of Feeding Assays for Insect Pest Management

Published on: May 26, 2023

1.7K

Effect of food on enteral absorption of quinidine

E Woo, D J Greenblatt

    Clinical Pharmacology and Therapeutics
    |February 1, 1980
    PubMed
    Abstract

    No abstract available in PubMed .

    More Related Videos

    The Caco-2 Cell Bioassay for Measurement of Food Iron Bioavailability06:34

    The Caco-2 Cell Bioassay for Measurement of Food Iron Bioavailability

    Published on: April 28, 2022

    5.5K
    Microsurgical Skills of Establishing Permanent Jugular Vein Cannulation in Rats for Serial Blood Sampling of Orally Administered Drug08:28

    Microsurgical Skills of Establishing Permanent Jugular Vein Cannulation in Rats for Serial Blood Sampling of Orally Administered Drug

    Published on: December 14, 2021

    9.9K

    Related Concept Videos

    Pharmacokinetics: Drug–Food and Drug–Viral Interactions01:26

    Pharmacokinetics: Drug–Food and Drug–Viral Interactions

    A drug interaction occurs when the concurrent use of another drug, food, or an external substance alters the pharmacological activity of a drug. This interaction can modify the action of the original drug, affecting its effectiveness and safety.Drug–food interactions are significant as they impact drug absorption, metabolism, and excretion. For example, grapefruit juice is a well-known disruptor of drug metabolism. It inhibits the cytochrome P450 3A4 enzyme, crucial for the metabolism of...
    188
    Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption01:23

    Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption

    Understanding the physiological differences in the pediatric population is crucial for effective pharmacotherapy. Neonates, infants, and children exhibit significant variations in gastric pH, gastric emptying time, intestinal transit time, and biliary function. These variations profoundly affect oral drug absorption, necessitating a nuanced approach to pediatric dosing.Neonates present with a unique physiological profile, having a gastric pH greater than 4 and faster and more irregular gastric...
    231
    Drug Absorption: Factors Affecting GI Absorption01:19

    Drug Absorption: Factors Affecting GI Absorption

    The process of oral drug absorption can be influenced by several factors. Weakly acidic drugs tend to be absorbed more readily from the stomach due to their nonionized state. However, absorption may be less efficient in the upper intestine, where drugs are often ionized. Interestingly, despite the stomach's apparent advantage for drug absorption, its mucous layer can hinder diffusion. Its surface area is also smaller than the intestine's, which can further slow down the absorption rate.
    5.8K
    Factors Influencing Drug Absorption: Disease States and Pharmacology01:25

    Factors Influencing Drug Absorption: Disease States and Pharmacology

    Multiple disease states can significantly influence the oral drug absorption process by affecting blood flow and the functionality of the gastrointestinal (GI) system. Various GI diseases, including conditions that alter GI motility, such as diarrhea, decreased acid secretions (achlorhydria), and infections, have been associated with reduced drug absorption.
    Substances such as alcohol and specific drugs, including antineoplastics, can also negatively impact drug absorption. For instance,...
    1.3K
    Factors Affecting Dissolution: Drug Permeability, Stability and Stereochemistry01:20

    Factors Affecting Dissolution: Drug Permeability, Stability and Stereochemistry

    Orally administered drugs primarily enter the systemic circulation via passive diffusion through the intestinal membranes. The drug's absorption is influenced by drug stability in the gastrointestinal GI tract, membrane permeability, the surface area available for absorption, luminal drug concentration, and residence time in the lumen. Drug permeability can be enhanced by adjusting the lipophilicity, polarity, or molecular size of the drug, promoting its passive transport across intestinal...
    480
    Routes of Drug Administration: Enteral01:18

    Routes of Drug Administration: Enteral

    Medications can be administered through the enteral route using liquids, capsules, or tablets.
    Enteral administration involves drug administration via the mouth in two ways: orally or sublingually.
    Unlike sublingually drugs, drugs that are taken orally pass through the gastrointestinal (GI) tract and get metabolized by the liver. Once metabolized, the drug is absorbed into the systemic circulation, reaching different body parts via the bloodstream. However, while passing through the stomach,...
    6.2K