Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Flow-volume loops in newborn infants

P H Wise, A N Krauss, S Waldman

    Critical Care Medicine
    |February 1, 1980
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Achieving net zero in a cluttered seascape: Policy gaps, conflicts and synergies.

    Marine pollution bulletin·2026
    Same author

    The skeletal consequences of epidural steroid injections: a literature review.

    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·2021
    Same author

    Positive selection of type 2 diabetes genotypes - the glycaemic threshold hypothesis.

    Medical hypotheses·2019
    Same author

    Assisted ventilation with bag and mask for neonates.

    Pediatric annals·2014
    Same author

    Transdisciplinary translational science and the case of preterm birth.

    Journal of perinatology : official journal of the California Perinatal Association·2012
    Same author

    Observation of two-neutrino double-beta decay in 136Xe with the EXO-200 detector.

    Physical review letters·2011

    Crying vital capacity (CVC) maneuvers in infants reveal flow-volume loops similar to adults with airway obstruction. While infants with hyaline membrane disease (HMD) showed trends, differences were not statistically significant.

    Area of Science:

    • Pediatric Pulmonology
    • Respiratory Physiology
    • Neonatal Medicine

    Background:

    • Infant respiratory mechanics are complex and not fully understood.
    • Flow-volume loops are a standard tool for assessing airway obstruction in adults.
    • Hyaline membrane disease (HMD) significantly impacts neonatal respiratory function.

    Purpose of the Study:

    • To characterize flow-volume loops during crying vital capacity (CVC) maneuvers in infants.
    • To compare these loops between healthy infants and those with hyaline membrane disease (HMD).
    • To identify factors influencing infant flow-volume loop morphology.

    Main Methods:

    • Obtained flow-volume loops using crying vital capacity (CVC) maneuvers.
    • Studied 31 infants, including 18 diagnosed with hyaline membrane disease (HMD).

    Related Experiment Videos

  • Analyzed loop characteristics, including inspiratory and expiratory flow rates and timing.

    • Main Results:

    • Infant flow-volume loops, both healthy and distressed, resembled adult patterns of variable intrathoracic airway obstruction.
    • Flow rates increased with increasing CVC in all infants.
    • Infants with HMD exhibited narrower inspiratory loops and delayed peak expiratory flow, though not statistically significant.

    Conclusions:

    • Infant flow-volume loops during CVC maneuvers can reflect airway obstruction.
    • Vocalizations, reduced lung recoil, and airway collapse may shape these loops.
    • Further research is needed to confirm significant differences in HMD infants.