Related Experiment Video

Updated: Aug 17, 2026

Vibrodissociation of Neurons from Rodent Brain Slices to Study Synaptic Transmission and Image Presynaptic Terminals
08:38

Vibrodissociation of Neurons from Rodent Brain Slices to Study Synaptic Transmission and Image Presynaptic Terminals

Published on: May 25, 2011

Electrogenic behavior of synaptic vesicles from Torpedo californica

R S Carpenter, S M Parsons

    The Journal of Biological Chemistry
    |January 25, 1978
    PubMed

    More Related Videos

    Measuring Synaptic Vesicle Endocytosis in Cultured Hippocampal Neurons07:30

    Measuring Synaptic Vesicle Endocytosis in Cultured Hippocampal Neurons

    Published on: September 4, 2017

    FM Dye Cycling at the Synapse: Comparing High Potassium Depolarization, Electrical and Channelrhodopsin Stimulation08:31

    FM Dye Cycling at the Synapse: Comparing High Potassium Depolarization, Electrical and Channelrhodopsin Stimulation

    Published on: May 24, 2018

    Related Concept Videos

    Synaptic Signaling01:12

    Synaptic Signaling

    Neurons communicate at synapses, or junctions, to excite or inhibit the activity of other neurons or target cells, such as muscles. Synapses may be chemical or electrical.
    Overview of Secretory Vesicles01:33

    Overview of Secretory Vesicles

    Secretory vesicles, also known as dense core vesicles (DCVs), are membrane-bound vesicles that transport secretory proteins, such as hormones or neurotransmitters. Regulated secretory vesicles transport proteins from the trans-Golgi network to the exterior of the cell. Proteins present in regulated secretory vesicles are required to be rapidly exocytosed in large amounts upon a specific stimulus.
    Various proteins regulate the aggregation of molecules inside the secretory vesicles. Chromogranins...
    Fusion of Secretory Vesicles with the Plasma Membrane01:26

    Fusion of Secretory Vesicles with the Plasma Membrane

    Proteins and neurotransmitters in secretory vesicles can be released from a cell upon vesicle docking, priming, and fusion with the plasma membrane. Vesicles are docked and primed in preparation for the quick exocytosis of their contents in response to a stimulus. The fusion process is mainly carried out by a SNAP Receptor or SNARE complex, consisting of synaptobrevin, syntaxin-1, and SNAP-25.
    In 1993, Jim Rothman proposed that the antiparallel pairing of vesicular and transmembrane SNAREs, or...
    Synaptic Signaling01:09

    Synaptic Signaling

    Neurons communicate at synapses, or junctions, to excite or inhibit the activity of other neurons or target cells, such as muscles. Synapses may be chemical or electrical.
    Most synapses are chemical, meaning an electrical impulse or action potential spurs the release of chemical messengers called neurotransmitters. The neuron sending the signal is called the presynaptic neuron, and the neuron receiving the signal is the postsynaptic neuron.
    The presynaptic neuron fires an action potential that...
    Chemical Synapses01:26

    Chemical Synapses

    Chemical synapses are specialized sites between two neurons or between a neuron and a non-neuronal cell like a muscle, glandular or sensory cell.
    Because chemical synapses depend on the release of neurotransmitter molecules from synaptic vesicles to pass on their signal, there is an approximately one millisecond delay between when the axon potential reaches the presynaptic terminal and when the neurotransmitter leads to opening of postsynaptic ion channels. Additionally, this signaling is...