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New compounds: derivatives of fluorene XXXVII: 9-substituted 3-nitrofluorenes
Journal of Pharmaceutical Sciences
|January 1, 1980
Abstract:
New 9-substituted 3-nitrofluorenes were prepared as potential intermediates in a study of modified electrophilicity and mutagenicity of the carcinogen 3-N,O-diacetylhydroxylaminofluorene. The reported derivatives, together with some already known 9-substituted 3-nitrofluorenes, were too unstable to survive the reducing conditions required to transform the nitro group to the corresponding hydroxylamine.