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Thromboembolism after insertion of the Mobin-Uddin caval filter
Surgery
|February 1, 1980
Summary
The Mobin-Uddin umbrella filter, used to prevent pulmonary emboli, showed incomplete protection in patients not on anticoagulants. A review found 12% experienced embolization after filter placement.
Area of Science:
- Vascular Surgery
- Cardiovascular Research
- Medical Device Safety
Background:
- The Mobin-Uddin umbrella filter is utilized to prevent pulmonary embolism.
- Anticoagulant therapy is often contraindicated in patients requiring filter placement.
- Assessing the efficacy of the Mobin-Uddin filter in this patient population is crucial.
Observation:
- A review of 41 patients who received a Mobin-Uddin umbrella filter over 5 years was conducted.
- Five patients (12%) experienced pulmonary embolization post-filter insertion.
- Autopsies revealed thrombus on the filter in 4 out of 7 patients, with one fresh embolus in the pulmonary artery.
Findings:
- The standard, non-heparin-impregnated Mobin-Uddin umbrella filter provides incomplete protection against pulmonary embolization.
- A significant complication rate of 12% for pulmonary embolization was observed in patients receiving the filter.
- Thrombus formation on the filter itself was a noted issue in autopsied cases.
Implications:
- The Mobin-Uddin umbrella filter may not be sufficient for patients unable to receive anticoagulants.
- Further research into alternative or modified filter designs is warranted.
- Clinical guidelines for filter use in high-risk patients may need revision.
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