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Amyloidosis presenting as priapism

D I Lapan, A R Graham, J L Bangert

    Urology
    |February 1, 1980
    PubMed

    Insights

    This study reports the first known case of amyloidosis presenting as painful priapism in a 65-year-old man. The condition progressed to widespread organ involvement and congestive heart failure.

    Area of Science:

    • Medicine
    • Pathology
    • Urology

    Background:

    • Amyloidosis is a rare condition involving abnormal protein deposits in organs.
    • Priapism, a persistent erection, can have various underlying causes.

    Observation:

    • A 65-year-old man presented with sudden, painful priapism.
    • Pathologic examination during surgery revealed extensive amyloid infiltration.

    Findings:

    • The patient subsequently developed purpura, organ enlargement, gastrointestinal bleeding, and congestive heart failure.
    • Postmortem examination confirmed widespread amyloidosis.

    Implications:

    • This case highlights priapism as a potential, albeit rare, initial presentation of amyloidosis.
    • Early recognition of amyloidosis is crucial for managing its systemic complications.

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