Immunoglobulin concentration in serum and seminal fluid from men with and without sperm-agglutinating antibodies

Serum and seminal fluid from infertile men with head-to-head (H-H) or tail-to-tail (T-T) sperm-agglutinating antibodies and fertile men devoid of sperm antibodies were examined for immunoglobulin (Ig)G, IgA, IgM, IgD, and IgE. Only IgG, IgA, and IgE were demonstrated in the seminal fluid. No statistically significant differences in the serum or seminal fluid immunoglobulin concentrations were found between the fertile and the two infertile groups of men examined.