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High-frequency High-resolution Echocardiography: First Evidence on Non-invasive Repeated Measure of Myocardial Strain, Contractility, and Mitral Regurgitation in the Ischemia-reperfused Murine Heart
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High-frequency High-resolution Echocardiography: First Evidence on Non-invasive Repeated Measure of Myocardial Strain, Contractility, and Mitral Regurgitation in the Ischemia-reperfused Murine Heart

Published on: July 10, 2010

Double diastolic murmur in mitral stenosis with atrial fibrillation and complete heart block

P Toutouzas, A Velimezis, D Avgoustakis

    British Heart Journal
    |January 1, 1980
    PubMed

    Insights

    A double diastolic murmur in mitral stenosis was linked to two distinct mitral valve movements during diastole. This finding supports the theory that valve motion against blood flow causes these murmurs.

    Area of Science:

    • Cardiology
    • Cardiac Physiology
    • Diagnostic Medicine

    Background:

    • Mitral stenosis, a narrowing of the mitral valve, can lead to complex auscultatory findings.
    • Atrial fibrillation and complete heart block are common comorbidities that affect cardiac rhythm and hemodynamics.

    Observation:

    • A patient presented with a double diastolic murmur, an unusual auscultatory finding.
    • Echocardiography revealed two separate opening and closing movements of the mitral valve within a single prolonged diastole.

    Findings:

    • A direct temporal correlation was established between the distinct mitral valve closing movements and the separate diastolic murmurs.
    • This observation supports the hypothesis that the mechanical motion of the mitral valve leaflets against diastolic blood flow generates these murmurs.

    Implications:

    • This study enhances the understanding of the pathophysiology of diastolic murmurs in complex cardiac conditions.
    • It highlights the diagnostic value of integrating echo-phonocardiography for elucidating murmur origins.
    • Further research can explore the clinical significance and management of such specific murmur types.

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