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Updated: Aug 23, 2026

Preterm EEG: A Multimodal Neurophysiological Protocol
Published on: February 18, 2012
Electrocardiographic abnormalities in infants and children with neurological injury
Insights
Electrocardiographic (ECG) abnormalities are common in children with central nervous system injuries. These neurogenic ECG changes, including arrhythmias, warrant close monitoring in pediatric intensive care units.
Area of Science:
- Pediatric critical care medicine
- Pediatric neurology
- Cardiology
Background:
- Central nervous system (CNS) injuries in children can result from trauma or neurosurgery.
- Electrocardiographic (ECG) changes are a potential complication following neurological insults.
- Pediatric intensive care unit (PICU) admissions often involve children with severe CNS injuries.
Purpose of the Study:
- To determine the frequency of ECG abnormalities in children admitted to the PICU with CNS injury.
- To identify specific types of ECG abnormalities observed.
- To highlight the clinical significance of neurogenic ECG changes in pediatric patients.
Main Methods:
- Retrospective analysis of ECG findings in 20 consecutive pediatric patients.
- Patients admitted to the PICU with CNS injury due to trauma or neurosurgery were included.
- ECG parameters and arrhythmias were systematically reviewed.
Main Results:
- 15 out of 20 children (75%) exhibited ECG abnormalities.
- Common abnormalities included prolonged qTc interval, U waves, and notched T waves.
- Ventricular arrhythmias were also observed in affected children.
Conclusions:
- Neurogenic ECG abnormalities are frequent in pediatric patients with CNS injury.
- The observed ECG changes can be serious and require attention.
- Routine ECG monitoring is recommended for all infants and children with neurological insults to detect potential neurogenic cardiac effects.
Abstract:
Electrocardiographic (ECG) abnormalities were found in 15 of 20 consecutive children (75%) admitted to the Pediatric ICU (PICU) with central nervous system injury produced by trauma or neurosurgical procedures. The ECG abnormalities included prolonged qTc, U waves, and notched T waves as well as ventricular arrhythmias. The high frequency and potential seriousness of this problem in infants and children suggests that neurogenic ECG changes should be looked for in all infants and children with neurological insults.
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