Related Experiment Videos
Insights
A rare case of diffuse infantile fibromatosis in a 15-month-old boy
Area of Science:
- Pediatric oncology
- Dermatopathology
- Skeletal muscle pathology
Background:
- Infantile fibromatosis is a rare soft tissue tumor affecting infants.
- Rapidly growing thigh tumors can mimic malignant neoplasms.
Observation:
- A 15-month-old boy presented with a rapidly growing right thigh mass.
- Macroscopic examination revealed an ill-defined lesion in the vastus medialis muscle.
- Histology showed fibroblast proliferation, fibrosis, inflammation, lymphoid follicles, and vascular proliferation.
Findings:
- The tumor was diagnosed as diffuse infantile fibromatosis.
- No recurrence was observed 1.5 years post-surgery.
Implications:
- This case highlights the importance of considering benign conditions in pediatric thigh masses.
- Accurate histological diagnosis is crucial for appropriate management and prognosis.
Abstract:
A boy 15 months old with diffuse infantile fibromatosis in the thigh is reported. A rapidly growing tumor in the right thigh was the only clinical manifestation, suggesting a malignant soft tissue tumor. Macroscopically, the lesion in the medial vastus muscle with an illdefined border gave a pepper and salt appearance. Histologically, the lesion was characterized by an abnormal proliferation of fibroblasts accompanied by some fibrosis, infiltration of chronic inflammatory cells, formation of lymphoid follicles, proliferation of capillaries and the presence of a small number of mature fat cells. No evidence of recurrence is found at present one and half years after operation.