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Lipolytic activity of some dermatophytes
Journal of Medical Microbiology
|February 1, 1980
Summary
Microsporum canis and Trichophyton mentagrophytes show high lipolytic activity, while T. rubrum has very little. This finding aids in identifying common dermatophytes based on their lipid-degrading capabilities.
Area of Science:
- Medical Mycology
- Dermatophyte Pathogenesis
Background:
- Dermatophytes are common fungal pathogens causing skin infections.
- Lipolytic enzymes play a role in fungal growth and tissue invasion.
Purpose of the Study:
- To assess and compare the lipolytic activities of four prevalent dermatophyte species.
- To explore the potential of lipolytic profiles for dermatophyte identification.
Main Methods:
- Culturing Epidermophyton floccosum, Microsporum canis, Trichophyton mentagrophytes, and T. rubrum on lipid-supplemented agar.
- Quantifying lipolytic activity by measuring zones of clearance around colonies.
Main Results:
- Microsporum canis exhibited the highest lipolytic activity.
- Trichophyton mentagrophytes and Epidermophyton floccosum showed moderate activity.
- Trichophyton rubrum displayed negligible lipolytic activity.
Conclusions:
- Lipolytic activity varies significantly among common dermatophytes.
- Lipase production can be a useful characteristic for differentiating dermatophyte species.
- Understanding lipolytic profiles may offer insights into dermatophyte virulence and treatment strategies.