Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Reactive hypoglycemia

D D Johnson, K E Dorr, W M Swenson

    JAMA
    |March 21, 1980
    PubMed
    Summary
    This summary is machine-generated.

    The five-hour oral glucose tolerance test (OGTT) is unreliable for diagnosing reactive hypoglycemia. Many patients with hypoglycemia symptoms may experience emotional disturbances instead.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    National Beef Quality Audit-2016: Transportation, mobility, and harvest-floor assessments of targeted characteristics that affect quality and value of cattle, carcasses, and by-products.

    Translational animal science·2020
    Same author

    National Beef Quality Audit-2016: Transportation, mobility, live cattle, and carcass assessments of targeted producer-related characteristics that affect value of market cows and bulls, their carcasses, and associated by-products.

    Translational animal science·2020
    Same author

    Methods of Chilling and Packaging of Beef, Pork and Lamb Variety Meats for Transoceanic Shipment: Microbiological Characteristics.

    Journal of food protection·2019
    Same author

    Methods of Chilling and Packaging of Beef, Pork and Lamb Variety Meats for Transoceanic Shipment: Physical and Sensory Characteristics.

    Journal of food protection·2019
    Same author

    Effect of Brahman genetics on myofibrillar protein degradation, collagen crosslinking, and tenderness of the longissimus lumborum.

    Journal of animal science·2018
    Same author

    National Beef Quality Audit - 2016: Survey of carcass characteristics through instrument grading assessments.

    Journal of animal science·2017
    Same journal

    WHO Issues Guidelines for Treating Ebola and Marburg Viruses.

    JAMA·2026
    Same journal

    FDA Approves Additional Naloxone Nasal Spray for Opioid Overdose.

    JAMA·2026
    Same journal

    HIV May Hide in More Cells Than Previously Thought-Here's What That Could Mean for a Cure.

    JAMA·2026
    Same journal

    US Dietary Supplement Use Increasing, Especially in Older Adults.

    JAMA·2026
    Same journal

    Heat Stress From Climate Change Surges Globally.

    JAMA·2026
    Same journal

    Strength Training Linked With Lower Cardiovascular Disease Risk in Women.

    JAMA·2026
    See all related articles

    Area of Science:

    • Endocrinology
    • Psychology
    • Clinical Medicine

    Background:

    • Reactive hypoglycemia is a condition characterized by symptoms of low blood sugar after meals.
    • The five-hour oral glucose tolerance test (OGTT) is commonly used to diagnose reactive hypoglycemia.
    • The reliability of the OGTT in diagnosing reactive hypoglycemia has been questioned.

    Purpose of the Study:

    • To assess the clinical characteristics and Minnesota Multiphasic Personality Inventory (MMPI) scores of patients undergoing a five-hour OGTT for reactive hypoglycemia evaluation.
    • To determine the relationship between hypoglycemic symptoms and plasma glucose levels during the OGTT.
    • To explore potential psychological factors contributing to symptoms suggestive of reactive hypoglycemia.

    Main Methods:

    • A cohort of 192 patients (twice as many women as men) undergoing a five-hour OGTT were evaluated.

    Related Experiment Videos

  • Clinical symptoms experienced during the OGTT were recorded.
  • Plasma glucose levels were measured during the test.
  • MMPI scores were compared to those of general medical patients.

    • Main Results:

    • One hundred twenty-nine patients reported symptoms like light-headedness, shakiness, diaphoresis, weakness, and fatigue.
    • Hypoglycemic symptoms were not correlated with plasma glucose nadir or glucose level descent rate.
    • Hypoglycemia was not detected during spontaneous symptom occurrence in 86 patients.
    • MMPI scores differed significantly from general medical patients, with both sexes showing a conversion V profile.

    Conclusions:

    • The five-hour OGTT appears to be an unreliable diagnostic tool for reactive hypoglycemia.
    • A significant proportion of patients with symptoms suggestive of hypoglycemia may have underlying emotional disturbances.
    • Further investigation into psychological factors is warranted for patients presenting with these symptoms.