[Extraosseous manifestations of primary hyperparathyroidism]

Nonfunctioning cysts were revealed in 2 of 23 patients with pathology of the parathyroid glands only. There was an expressed clinical picture of primary hyperparathyroidism in two patients with carcinoma, 3 with hyperplasia, and in 16 cases with adenoma of the parathyroid glands. Extraosseous manifestations were chiefly noted in the patients with adenoma of the parathyroid glands (in 7 of 16). In many cases they were the first, and in some the only manifestations of the disease. In two cases the disease coursed as a persistently relapsing urolithiasis (the patients had had nephrectomy), in four as peptic ulcer of the stomach or duodenum (resection of the stomach was performed in two cases), and in one case the neurological symptoms prevailed. Thus, extraosseous manifestations of primary hyperparathyroidism were not rare. All cases of persistent urolithiasis, and peptic ulcer of the stomach are subject to special examination for hyperparathyroidism.