Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Roentgenographic changes during long-term diphenylhydantoin therapy

E S McCrea, C V Rao, J N Diaconis

    Southern Medical Journal
    |March 1, 1980
    PubMed
    Summary

    Long-term use of diphenylhydantoin (Dilantin), an anticonvulsant, can cause unrecognized roentgenographic changes. These radiographic findings may help physicians identify diphenylhydantoin-induced diseases.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    <i>Lhb</i><sup>-/-</sup><i>Lhr</i><sup>-/-</sup> Double Mutant Mice Phenocopy <i>Lhb</i><sup>-/-</sup> or <i>Lhr</i><sup>-/-</sup> Single Mutants and Display Defects in Leydig Cells and Steroidogenesis.

    International journal of molecular sciences·2022
    Same author

    Anisotropic bianchi V cosmological model in Scale Covariant Theory of Gravitation with a time-variable deceleration parameter.

    Heliyon·2020
    Same author

    Targeting the paracrine hormone-dependent guanylate cyclase/cGMP/phosphodiesterases signaling pathway for colorectal cancer prevention.

    Seminars in cancer biology·2018
    Same author

    Neutralization of <i>Naja naja</i> venom induced lethality, edema and myonecrosis by ethanolic root extract of <i>Coix lacryma-jobi</i>.

    Toxicology reports·2017
    Same author

    Protective Effects of Human Chorionic Gonadotropin Against Breast Cancer: How Can We Use This Information to Prevent/Treat the Disease?

    Reproductive sciences (Thousand Oaks, Calif.)·2017
    Same author

    Systemic chromosome instability in Shugoshin-1 mice resulted in compromised glutathione pathway, activation of Wnt signaling and defects in immune system in the lung.

    Oncogenesis·2016

    Area of Science:

    • Radiology
    • Pharmacology
    • Neurology

    Background:

    • Diphenylhydantoin (Dilantin) is a widely used and effective anticonvulsant medication.
    • Clinical complications associated with long-term diphenylhydantoin use are recognized but can be numerous.
    • Subtle, clinically non-apparent adverse effects may occur.

    Purpose of the Study:

    • To document and describe the roentgenographic changes associated with long-term diphenylhydantoin (Dilantin) therapy.
    • To highlight radiographic findings that may indicate diphenylhydantoin-induced disease.
    • To increase physician awareness of potential radiographic manifestations of Dilantin toxicity.

    Main Methods:

    • Review of radiographic findings in patients with a history of long-term diphenylhydantoin use.

    Related Experiment Videos

  • Correlation of roentgenographic changes with clinical presentation and duration of therapy.
  • Analysis of specific radiological patterns indicative of diphenylhydantoin-related complications.

    • Main Results:

    • Identification of specific, often subtle, roentgenographic abnormalities in patients on long-term diphenylhydantoin.
    • Demonstration of radiological changes not always apparent through routine clinical examination.
    • Association of certain radiographic findings with diphenylhydantoin-induced pathology.

    Conclusions:

    • Roentgenographic examination can reveal significant changes in patients using diphenylhydantoin long-term.
    • These radiological findings serve as crucial indicators for diagnosing diphenylhydantoin-induced diseases.
    • Awareness of these radiographic signs is essential for timely clinical recognition and management.