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Related Experiment Videos

Aflatoxicosis in swine: a review

J R Clarkson

    Veterinary and Human Toxicology
    |February 1, 1980
    PubMed
    Summary

    Aflatoxins negatively impact swine production by weakening immunity and increasing mortality, especially in young pigs. Management strategies and new field tests can help mitigate these chronic effects.

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    Area of Science:

    • Animal Science
    • Toxicology
    • Agricultural Science

    Background:

    • Chronic aflatoxin exposure can impair swine immune function, increasing disease susceptibility and mortality.
    • Younger pigs are more vulnerable to aflatoxin-induced damage than older swine.
    • Aflatoxin contamination, particularly from corn and cottonseed meal, is a significant issue in the Southeastern United States.

    Purpose of the Study:

    • To investigate the chronic effects of aflatoxins on swine production efficiency.
    • To identify factors influencing individual pig susceptibility to aflatoxins.
    • To explore management strategies for aflatoxin prevention and reduction.

    Main Methods:

    • The study assessed the impact of aflatoxins on immune response, disease susceptibility, and stress resistance in swine.
    • Age-related susceptibility to aflatoxin damage was evaluated.
    • Field surveys utilizing a quantitative aflatoxin test were conducted on suspected feed sources.

    Main Results:

    • Aflatoxins reduce swine immune response, leading to increased disease susceptibility and mortality.
    • Younger pigs exhibit significantly higher susceptibility to aflatoxin toxicity.
    • Management practices play a crucial role in preventing and reducing aflatoxin levels in animal feed.

    Conclusions:

    • Chronic aflatoxin exposure poses a significant threat to swine production efficiency and animal health.
    • Age is a critical factor in determining pig susceptibility to aflatoxins.
    • Development of field tests and decontamination processes offers potential solutions for managing aflatoxin contamination in swine feed.

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