Related Experiment Video
Updated: Aug 11, 2026

In Vivo and Ex Vivo Approaches to Study Ovarian Cancer Metastatic Colonization of Milky Spot Structures in Peritoneal Adipose
Published on: October 14, 2015
[Ovarian cancer metastasis to the greater omentum]
Abstract:
The peculiar features of ovarian cancer metastasization in the greater omentum have been studied. A retrospective analysis of the data on 268 operated patients with serous cystadenocarcinoma of the ovary and a perspective study pertaining to 99 patients with ovarian malignant tumors of different histotypes enabled detecting metastases in the greater omentum in 73.9% and 63.6% of cases accordingly. An intensity of metastatic dissemination was dependent on stage, the presence of exudates in the abdominal and pleural cavities but was independent on patients' age. High incidence of metastatic involvement of the omentum, the recognition of micrometastases, detected only histologically in 15.9% of patients, allowed a recommendation to be substantiated for the mandatory removal of the greater omentum at all clinical stages of ovarian cancer.
Related Concept Videos
Oogenesis
Metastasis
Epithelial-to-Mesenchymal Transition
The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...
Metastasis
Epithelial-to-Mesenchymal Transition
The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...
Peritoneum
Anatomy of the Peritoneum
The peritoneum is divided into two layers: the parietal peritoneum and the visceral...

