Concentration and purification of human rabies vaccines : results

Concentration of two types of rabies tissue culture vaccine has been realized with Amicon hollow fibers. The coefficient of purification obtained on Sepharose 6B chromatography is 2,3 to 4,6 with a recuperation of 25% to 30% of the haemagglutination power for one of the vaccines. The control of glycoprotein contents has been realized by means of classical technics as well as the rapid immunoenzymatic test. (I.E.T.).