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Updated: Feb 10, 2026
04:29
A Modified Simple Method for Induction of Myocardial Infarction in Mice
Published on: December 3, 2021
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Summary
Flumethasone (FLU) and prostaglandin F2 alpha-THAM salt (PGF) effectively induced parturition in ewes. Both treatments significantly increased lambing rates and shortened gestation compared to controls.
Area of Science:
- Veterinary Medicine
- Reproductive Biology
- Animal Science
Background:
- Induction of parturition is crucial for managing lambing in sheep production.
- Identifying effective and timely methods for inducing labor is essential for flock management.
Purpose of the Study:
- To evaluate the efficacy of flumethasone (FLU) and prostaglandin F2 alpha-THAM salt (PGF) in inducing parturition in ewes.
- To compare the lambing rates and interval to parturition following FLU and PGF treatments.
Main Methods:
- 117 ewes were treated on day 141 of gestation with either FLU (2 mg), PGF (15 mg), or saline (control).
- Parturition events and the time from treatment to lambing were recorded for each ewe.
Main Results:
- 89% of FLU-treated ewes and 33% of PGF-treated ewes lambed within 72 hours.
- Both FLU and PGF treatments resulted in significantly higher lambing rates within 72 hours compared to the control group (P < .01).
- The interval from treatment to parturition was significantly shorter for ewes treated with FLU (P < .01) and PGF (P < .05) compared to saline controls.
Conclusions:
- Flumethasone and prostaglandin F2 alpha-THAM salt are effective agents for inducing parturition in ewes.
- Both treatments offer a viable option for synchronizing lambing and managing reproductive cycles in sheep, with flumethasone showing a higher immediate response.
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