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Synthesis and biological activity of some 15-oxaestranes
Journal of Medicinal Chemistry
|March 1, 1980
Abstract:
The estrogenic activity of orally administered 15-oxaestrone was evaluated by the uterotropic assay in rats and was found to be 12 times greater than that of estrone. In addition, several analogues of 15-oxaestrone were prepared and their estrogenic potency was determined.