Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Recurrent hematuria in children]

R Dumas, P Baldet, S Bascoul

    Archives Francaises De Pediatrie
    |August 1, 1978
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Calcified glomus tumor of the shoulder. A case report.

    Chirurgie de la main·2008
    Same author

    [Langherans' cell histiocytosis: a case report].

    Journal de radiologie·2006
    Same author

    Acinar cell carcinoma of the pancreas in a young patient with cells immunoreactive for somatostatin.

    Histopathology·2006
    Same author

    [Carcinoma with false negative mammogram: when and how?].

    Journal de radiologie·2005
    Same author

    A nationwide study of granulosa cell tumors in pre- and postpubertal girls: missed diagnosis of endocrine manifestations worsens prognosis.

    Journal of pediatric endocrinology & metabolism : JPEM·2005
    Same author

    Time-course of tomato whole-plant respiration and fruit and stem growth during prolonged darkness in relation to carbohydrate reserves.

    Annals of botany·2003
    Same journal

    A case of congenital myatonia (Oppenheim's disease).

    Archives francaises de pediatrie·2010
    Same journal

    A case of severe haemolytic anemia anemia.

    Archives francaises de pediatrie·2010
    Same journal

    On the acute anemia of the newborn.

    Archives francaises de pediatrie·2010
    Same journal

    Intermittent jaundice; intrahepatic bile duct agenesis.

    Archives francaises de pediatrie·2010
    Same journal

    Osteomyelitis with acute staphylococcus aureus with septicemia and pericarditis cured without surgery by iodo-sulfonamide therapy.

    Archives francaises de pediatrie·2010
    Same journal

    Mickulicz syndrome and hepatomegaly during a diabetes mellitus.

    Archives francaises de pediatrie·2010
    See all related articles

    Recurrent macroscopic hematuria in children can stem from various kidney disorders, including Berger's disease and hereditary nephritis like Alport's syndrome. Early diagnosis and understanding the underlying cause are crucial for managing these conditions.

    Area of Science:

    • Pediatric Nephrology
    • Glomerular Diseases
    • Hereditary Kidney Diseases

    Background:

    • Recurrent macroscopic hematuria is a significant clinical presentation in pediatric nephrology.
    • Identifying the underlying etiology is crucial for prognosis and management.
    • Previous studies have highlighted various causes, but a comprehensive overview in a pediatric cohort is valuable.

    Purpose of the Study:

    • To investigate the diverse causes of recurrent macroscopic hematuria in a cohort of 23 children.
    • To characterize the clinical and pathological findings associated with different kidney disorders.
    • To differentiate between acquired and hereditary causes of hematuria.

    Main Methods:

    • Clinical observation of 23 children with recurrent macroscopic hematuria.

    Related Experiment Videos

  • Light microscopy for glomerular lesions.
  • Immunofluorescence for mesangial deposits (IgG, IgA).
  • Electron microscopy for basement membrane abnormalities.
  • Family history assessment for hereditary nephritis.

    • Main Results:

    • Six children had Berger's disease (IgA nephropathy) with hematuria post-infection.
    • Ten children exhibited hereditary nephritis, including Alport's syndrome (5 cases) and isolated hereditary nephritis (5 cases).
    • Electron microscopy confirmed Alport's syndrome and showed less severe basement membrane changes in isolated hereditary nephritis.
    • Seven children had no specific etiology identified.

    Conclusions:

    • Recurrent macroscopic hematuria in children can be attributed to IgA nephropathy, hereditary nephritis (including Alport's syndrome), or idiopathic causes.
    • Infection-triggered hematuria suggests Berger's disease, while family history and specific ultrastructural findings point to hereditary nephritis.
    • Further investigation is warranted for cases with no clear etiology.