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[Electrolyte balance in a case of congenital chloride diarrhea]
Archives Francaises De Pediatrie
|August 1, 1978
Insights
Congenital chloride diarrhea is a rare condition causing chronic watery diarrhea from birth. This case highlights significant fecal chloride loss and its link to electrolyte imbalances.
Area of Science:
- Pediatric Gastroenterology
- Electrolyte and Acid-Base Disorders
Background:
- Congenital chloride diarrhea (CCD) is a rare inherited disorder of intestinal ion transport.
- It presents in infancy with persistent watery diarrhea and electrolyte disturbances, primarily metabolic alkalosis.
Observation:
- A 9-year-old boy with a history of intractable chronic diarrhea and large watery stools since birth was evaluated.
- The patient presented with symptoms consistent with significant fluid and electrolyte loss.
Findings:
- Balance studies confirmed substantial fecal chloride loss in the patient.
- A direct correlation was observed between chloride intake and the fecal excretion of electrolytes, confirming the pathophysiology of CCD.
Implications:
- This case underscores the importance of recognizing congenital chloride diarrhea in pediatric patients with chronic diarrhea and metabolic alkalosis.
- Accurate diagnosis and management are crucial for preventing severe electrolyte derangements and ensuring adequate growth and development.
Abstract:
A case of congenital chloride diarrhoea with metabolic alkalosis is reported in a 9-year-old boy who has intractable chronic diarrhoea with large watery stools from birth. Balance studies confirm the high fecal loss of chloride and the close relationship between chloride intake and fecal losses of electrolytes.