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Hemiplegic spasticity: neurophysiologic studies

J Somerville, P Ashby

    Archives of Physical Medicine and Rehabilitation
    |December 1, 1978
    PubMed
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    In normal subjects and hemiplegia patients, researchers studied reflex pathways using Achilles tendon vibration. Hemiplegia patients showed less late inhibition, suggesting a potential cause for exaggerated reflexes.

    Area of Science:

    • Neuroscience
    • Motor Control
    • Clinical Neurology

    Background:

    • Segmental reflex pathways are crucial for motor control.
    • Patients with hemiplegia often exhibit exaggerated reflexes.
    • Understanding reflex modulation is key to neurological rehabilitation.

    Purpose of the Study:

    • To investigate the excitability of segmental reflex pathways in normal subjects and hemiplegic patients.
    • To examine the effects of Achilles tendon vibration on the monosynaptic H reflex.
    • To identify potential differences in inhibitory mechanisms between healthy individuals and those with hemiplegia.

    Main Methods:

    • Conditioning the monosynaptic H reflex using a 200 msec vibration burst applied to the tendo Achilles.
    • Recording reflex responses in soleus motoneurons in both normal subjects and hemiplegic patients.

    Related Experiment Videos

  • Quantifying short-latency facilitation and longer-latency inhibition.
  • Main Results:

    • In normal subjects, vibration induced short-latency facilitation followed by longer-latency inhibition of soleus motoneurons.
    • Hemiplegic patients showed a similar short-latency facilitation.
    • However, hemiplegic patients exhibited significantly reduced longer-latency inhibition compared to normal subjects.

    Conclusions:

    • A diminished inhibitory mechanism in patients with hemiplegia may contribute to their exaggerated reflexes.
    • These findings highlight potential targets for therapeutic interventions in hemiplegia.
    • Modulation of reflex pathways offers insights into motor recovery after neurological injury.