Jove
Visualize
Contact Us

Related Experiment Videos

Filterable cell-associated cryptic bacterial forms in immunologic renal diseases

G J Domingue

    Urological Survey
    |February 1, 1980
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Cryptic bacterial infection in chronic prostatitis: diagnostic and therapeutic implications.

    Current opinion in urology·2006
    Same author

    Prostatitis.

    Clinical microbiology reviews·1998
    Same author

    Bacterial persistence and expression of disease.

    Clinical microbiology reviews·1997
    Same author

    Bacterial infection in prostatodynia.

    The Journal of urology·1995
    Same author

    Dormant microbes in interstitial cystitis.

    The Journal of urology·1995
    Same author

    Antibodies to Escherichia coli 06 porins cross-react with urinary pathogens.

    Immunobiology·1994
    Same journal

    Physical and chemical characteristics of renal stone matrix.

    Urological survey·1981
    Same journal

    A urological perspective.

    Urological survey·1981
    Same journal

    Current concepts of pain mechanisms.

    Urological survey·1981
    Same journal

    Renal adenocarcinoma.

    Urological survey·1980
    Same journal

    Primary aldosteronism--a review.

    Urological survey·1980
    Same journal

    Surgical treatment of renovascular hypertension.

    Urological survey·1980
    See all related articles
    JoVE
    x logofacebook logolinkedin logoyoutube logo
    ABOUT JoVE
    OverviewLeadershipBlogJoVE Help Center
    AUTHORS
    Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
    LIBRARIANS
    TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
    RESEARCH
    JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
    EDUCATION
    JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
    Terms & Conditions of Use
    Privacy Policy
    Policies

    Certain nephritis patients harbor filterable bacteria, missed by standard cultures, potentially causing kidney disease. These bacterial forms or their complexes may initiate immunopathologic events in renal diseases.

    Area of Science:

    • Nephrology
    • Microbiology
    • Immunology

    Background:

    • Nephritis is often idiopathic, with unknown etiologic agents.
    • Conventional culture techniques may fail to detect certain microbial forms.
    • Filterable bacterial forms in patient samples are not widely recognized as disease factors.

    Purpose of the Study:

    • To investigate the presence of filterable bacterial forms in nephritis patients.
    • To explore the potential role of these overlooked bacteria in immunologic renal diseases.
    • To hypothesize the mechanisms by which these bacteria might initiate kidney pathology.

    Main Methods:

    • Analysis of blood and urine samples from nephritis patients.
    • Utilizing filtration techniques (0.22 mu.) to isolate bacterial forms.

    Related Experiment Videos

  • Comparison with conventional culture methods to identify missed organisms.

    • Main Results:

    • Detection of filterable bacterial forms in blood and urine of nephritis patients.
    • These bacterial forms were not identified by standard culture methods.
    • Evidence suggests these organisms are overlooked by current diagnostic approaches.

    Conclusions:

    • Filterable bacteria may be a novel etiologic factor in certain nephritis cases.
    • These cryptic bacterial forms, or associated antigen complexes, could trigger autoimmune responses in renal diseases.
    • Further research is warranted to confirm the role of these bacteria in immunopathologic renal conditions.