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[Clinical biochemical changes in ischemic heart disease: hyperuricemia as a risk factor]

V Lin'ova, S Mantov, B Shakhov

    Vutreshni Bolesti
    |January 1, 1980
    PubMed

    Insights

    Elevated uric acid levels are common in patients with ischemic heart disease (IHD). This study suggests hyperuricemia may be a risk factor for IHD, linked to fats, cholesterol, and protein levels.

    Area of Science:

    • Cardiology
    • Biochemistry

    Context:

    • Ischemic heart disease (IHD) affects a significant portion of the population.
    • Understanding risk factors for IHD is crucial for prevention and management.

    Purpose:

    • To investigate the relationship between uric acid levels and ischemic heart disease (IHD).
    • To explore correlations between uric acid and other biomarkers in IHD patients.

    Summary:

    • A study of 160 patients with IHD revealed elevated uric acid in 51.5%.
    • Positive correlations were observed between uric acid and total fats, cholesterol, and total protein.
    • Reverse correlations were found between uric acid and alpha 2-globulin, beta, and gamma globulin fractions.

    Impact:

    • Findings suggest hyperuricemia could be an independent risk factor for IHD.
    • This research may inform future diagnostic and therapeutic strategies for IHD.

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