Related Experiment Video
Updated: Aug 18, 2026
A Hyperandrogenic Mouse Model to Study Polycystic Ovary Syndrome
Published on: October 2, 2018
Correlations between adenohypophyseal weight, serum polyphenol oxidase activity (ceruloplasmin) and hypothalamic
Abstract:
Serum polyphenol oxidase activity (ceruloplasmin) and the hypothalamic ascorbic acid concentration were determined in control rats and rats given estradiol for 2-6 months. A significant positive correlation (r = 0.5948, p less than 0.001) was found between adenohypophyseal weight and the ceruloplasmin level and a negative correlation between adenohypophyseal weight and the ascorbic acid concentration in the hypothalamus (r = -0.5728, p less than 0.01) and between the hypothalamus ascorbic acid concentration and the ceruloplasmin level (r = -0.7059, p less than 0.01). The ways in which an increase in serum polyphenol oxidase activity might modulate the adenohypophyseal reaction to estradiol are discussed.
