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Bis-trimethylsilylcefamandole: an unusually stable trimethylsilyl-intermediate
The Journal of Antibiotics
|January 1, 1980
Abstract:
The preparation of crystalline bis-trimethylsilylcefamandole (7) and its utility in the preparation and purification of cefamandole are described. Although stable to solvolysis in isopropyl alcohol, 7 underwent smooth conversion to cefamandole in the presence of water, methanol, or ethanol.
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