Radiation-induced fibrosarcoma of the head and neck

Primary fibrosarcoma of the neck is uncommon; radiation-induced similar lesions are rare. They might start as irradiation fibromatosis akin to extraabdominal desmoids, but they tend to kill by local invasion rather than by distant dissemination. The literature has been briefly reviewed with a short discussion of clinical and pathological features of both the primary (de novo) and the secondary (radiation-induced) types of fibrosarcoma. Two cases of post-irradiation fibrosarcoma of the neck are presented.