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Related Experiment Videos

Physiological tremor enhanced by manoeuvres affecting the segmental stretch reflex

R R Young, K E Hagbarth

    Journal of Neurology, Neurosurgery, and Psychiatry
    |March 1, 1980
    PubMed
    Summary

    Physiological tremor in healthy subjects can be amplified by enhancing the stretch reflex servo. This study investigated how increased stretch reflex efficacy and altered muscle properties influence tremor generation.

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    Area of Science:

    • Neuroscience
    • Human Physiology
    • Motor Control

    Background:

    • Recent evidence suggests physiological tremor is amplified by positive feedback from the segmental stretch reflex.
    • Understanding the mechanisms of tremor enhancement is crucial for neurological research.

    Purpose of the Study:

    • To investigate if tremorogenic effects are partly due to increased stretch reflex servo efficacy.
    • To explore how various maneuvers and procedures affect finger and hand tremor in healthy individuals.

    Main Methods:

    • Recorded mechanical events during tremor and muscle twitches.
    • Measured EMG activity from wrist and finger flexor muscles.
    • Recorded discharges from primary spindle endings in muscles.

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    Main Results:

    • Physiological tremor is enhanced by maneuvers increasing stretch reflex gain (e.g., Jendrassik maneuver).
    • Tremor also increases with enhanced contrast in spindle firing during tremor phases, improving reflex modulation.
    • Altering muscle mechanical properties (isoproterenol, fatigue) and applying spindle stimuli (vibrations) during stretch phases also enhance tremor.

    Conclusions:

    • Increased stretch reflex efficacy contributes to physiological tremor enhancement.
    • Modulating spindle firing contrast and muscle mechanical properties are key factors in tremor generation.
    • External perturbations and pseudo-myoclonic jerks can accentuate physiological tremor.