[Renal hemodynamics in arteriosclerosis and its changes under increased arterial pressure]

Renal hemodynamics were studied in patients suffering from atherosclerosis with predominant localization of the process not in the renal artery (in patients with chronic ischemic heart disease) and with normal or periodically increased arterial pressure (to 160/95 mm Hg). The data obtained were compared with the findings in groups of healthy persons and patients with III stage hypertensive disease. A history of myocardial infarction was the criterion of the presence of atherosclerosis. It was established that the changes progress from age involution to those more pronounced in atherosclerosis and are of a quantitative character; they are of a similar trend. An increase of arterial pressure contributes to deterioration in the blood supply to the kidneys, besides marked quantitative changes (mainly due to increased resistance of the renal vessels) new qualitative shifts occur (increase in the filtration fraction) which aggravate renal hemodynamics and thus contribute to the fixation of the nephrogenic factor in the further development of arterial hypertension.