The conditions of mitral valve closure

Due to inertia of the mitral blood flow the closure of the mitral valve is delayed for a certain time after the atrioventricular pressure cross over. This delay is investigated by means of dimensional analysis. A nondimensional number occurring in this analysis is taken from a reported dog experiment and the analysis is then used to determine the conditions of mitral valve closure in man, both during rest and during exercise. The results show that rather high ventricular pressures are obtained during exercise before the mitral valve closes.