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Related Experiment Videos

Management of abdominal aortic aneurysm

I C Gordon-Smith, E W Taylor, A N Nicolaides

    The British Journal of Surgery
    |December 1, 1978
    PubMed
    Summary

    Perioperative antibiotics significantly reduced early graft infections and deaths in abdominal aortic aneurysm surgery. This study highlights their crucial role in improving patient outcomes for vascular procedures.

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    Despeckle Filtering for Multiscale Amplitude-Modulation Frequency-Modulation (AM-FM) Texture Analysis of Ultrasound Images of the Intima-Media Complex.

    International journal of biomedical imaging·2014

    Area of Science:

    • Vascular Surgery
    • Surgical Outcomes
    • Infectious Disease in Surgery

    Background:

    • Abdominal aortic aneurysm (AAA) repair is a major surgical undertaking with significant associated risks.
    • Historically, outcomes for ruptured or leaking AAAs were poor, and graft infection remains a serious complication.
    • Evolving surgical techniques and perioperative care have aimed to improve patient survival and reduce complications.

    Purpose of the Study:

    • To evaluate the outcomes of surgical repair for abdominal aortic aneurysms over a 9-year period.
    • To assess the impact of changing surgical techniques, specifically the inlay graft, on mortality.
    • To determine the incidence and impact of early graft infection and the role of perioperative antibiotics.

    Main Methods:

    • Retrospective analysis of 245 patients undergoing abdominal aortic aneurysm surgery between 1969 and 1977.

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  • Comparison of outcomes between elective and emergency (leaking/ruptured) cases.
  • Evaluation of surgical techniques (excision-replacement vs. inlay grafts) and the use of perioperative antibiotics.

    • Main Results:

    • Hospital mortality for leaking/ruptured aneurysms decreased from 77% to 30% over the study period.
    • Elective AAA repair had an average hospital mortality of 9.3%, with no deaths in the final 51 cases.
    • Early graft infection occurred in 3.7% of patients (9 deaths), predominantly in the inlay graft group without perioperative antibiotics (8/9 deaths).

    Conclusions:

    • The inlay technique for abdominal aortic aneurysm repair, while used more frequently, was associated with higher rates of early graft infection.
    • Perioperative antibiotic prophylaxis was strongly associated with a reduction in early graft infections.
    • Routine use of perioperative antibiotics for arterial prosthetic graft patients was implemented in July 1976 due to these findings.