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Infected prosthetic grafts

R E Casali, W E Tucker, B W Thompson

    Archives of Surgery (Chicago, Ill. : 1960)
    |May 1, 1980
    PubMed
    Summary
    This summary is machine-generated.

    Prompt surgical intervention is crucial for managing infected prosthetic grafts. Early diagnosis and appropriate treatment, often involving extra-anatomical bypass and graft removal, improve patient outcomes and reduce mortality.

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    Area of Science:

    • Vascular Surgery
    • Infectious Disease Management

    Background:

    • Prosthetic arterial reconstructions carry a risk of infection.
    • A series of 652 prosthetic arterial reconstructions included 20 infected grafts.

    Observation:

    • The groin was the most common site of infection.
    • Local wound management often failed, particularly when the suture line was involved.
    • Graft excision without revascularization led to high rates of amputation and mortality.

    Findings:

    • Early procrastination in treatment increased morbidity and mortality.
    • Complete aortofemoral graft excision with extra-anatomical revascularization was uniformly fatal.
    • Localized infections may be treated with antibiotic irrigation.
    • Extensive infections necessitate extra-anatomical bypass followed by graft removal.

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    Implications:

    • Prompt operative assessment of infection extent is vital.
    • A staged approach involving extra-anatomical bypass before infected graft removal is recommended for extensive infections.
    • Effective management strategies can mitigate the severe consequences of prosthetic graft infections.