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[Renal vein thrombosis]
Boletin Medico Del Hospital Infantil De Mexico
|March 1, 1980
Summary
Renal vein thrombosis in children often presents with metabolic acidosis and electrolyte imbalances, not typically linked to perinatal factors. Disseminated intravascular coagulation was confirmed in some cases.
Area of Science:
- Pediatric Pathology
- Nephrology
- Hematology
Context:
- Retrospective analysis of 21 autopsy protocols (1967-1977) concerning pediatric renal vein thrombosis.
- Investigated bilateral (16 cases) and unilateral (5 cases) presentations.
- Examined correlations with pre- and perinatal backgrounds.
Purpose:
- To characterize the pathological findings and associated conditions in pediatric renal vein thrombosis.
- To identify potential etiological factors and clinical presentations.
- To assess the prevalence of disseminated intravascular coagulation and classic clinical triads.
Summary:
- Renal vein thrombosis in children showed no correlation with pre- or perinatal background factors.
- Consistent findings included electrolyte imbalance and severe metabolic acidosis.
- Disseminated intravascular coagulation was pathologically confirmed in 6 cases; the classic triad was infrequent.
Impact:
- Highlights the metabolic derangements associated with pediatric renal vein thrombosis.
- Underscores the importance of considering coagulopathies like disseminated intravascular coagulation.
- Suggests that the classic clinical presentation is not a reliable indicator in pediatric cases.