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[Renal vein thrombosis]

V M Ortíz Méndez, R Bonilla Aguirre, C Olvera Hidalgo

    Boletin Medico Del Hospital Infantil De Mexico
    |March 1, 1980
    PubMed
    Summary
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    Renal vein thrombosis in children often presents with metabolic acidosis and electrolyte imbalances, not typically linked to perinatal factors. Disseminated intravascular coagulation was confirmed in some cases.

    Area of Science:

    • Pediatric Pathology
    • Nephrology
    • Hematology

    Context:

    • Retrospective analysis of 21 autopsy protocols (1967-1977) concerning pediatric renal vein thrombosis.
    • Investigated bilateral (16 cases) and unilateral (5 cases) presentations.
    • Examined correlations with pre- and perinatal backgrounds.

    Purpose:

    • To characterize the pathological findings and associated conditions in pediatric renal vein thrombosis.
    • To identify potential etiological factors and clinical presentations.
    • To assess the prevalence of disseminated intravascular coagulation and classic clinical triads.

    Summary:

    • Renal vein thrombosis in children showed no correlation with pre- or perinatal background factors.
    • Consistent findings included electrolyte imbalance and severe metabolic acidosis.

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  • Disseminated intravascular coagulation was pathologically confirmed in 6 cases; the classic triad was infrequent.

    • Impact:

    • Highlights the metabolic derangements associated with pediatric renal vein thrombosis.
    • Underscores the importance of considering coagulopathies like disseminated intravascular coagulation.
    • Suggests that the classic clinical presentation is not a reliable indicator in pediatric cases.