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Updated: Aug 17, 2026

08:44
A High-Throughput In Situ Method for Estimation of Hepatocyte Nuclear Ploidy in Mice
Published on: April 19, 2020
[Polyploidization of hepatocytes under different regimens of rat liver exposed to CCl4]
Biulleten' Eksperimental'Noi Biologii I Meditsiny
|January 1, 1980
Abstract:
Polyploidization of hepatocytes in albino rats subjected to continuous and intermittent exposure to CCl4 has been studied karyometrically. It has been shown that polyploidization as a response to the exposure of chlorderivatives of hydrocarbons is determined by hepatotoxin toxicity related to the number of chlorine atoms in the molecule and to the character of the exposure involving route, dose and regimen of exposure.

