Solitary extramedullary plasmacytoma of the upper respiratory and digestive tracts

The diagnosis, treatment and follow-up data for patients with malignant solitary extramedullary plasmacytoma of the upper respiratory and digestive tracts for the period from 1949 to 1975 are presented. The neoplasm developed in the nasal fossae in 3 patients; in the maxillary sinuses in 2; in the supraglottic region in 1; and in the tonsillar fossa in 1. Curative radiation therapy is recommended after the diagnosis is established by biopsy examination only. In the present series, this practice resulted in complete regression of the tumors in all of the patients, with restoration of functions without local recurrence. In no case did the local disease transform into systemic myeloma.