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Spontaneous reversal of ethinyl estradiol-induced cholestasis in the rat

R Tritapepe, C Di Padova, P Rovagnati

Experientia

|May 15, 1980

Abstract:

The spontaneous reversal ethinyl estradiol-induced cholestasis has been documented 7 days after the last estrogen administration in the rat. This finding supports the hypothesis that estrogens produce only a transient functional failure of the hepatocytic structures responsible for bile secretion.

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