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Liquid chromatography with amperometric detection for determinging phenolic preservatives
Journal - Association of Official Analytical Chemists
|January 1, 1980
Summary
This study presents a fast and sensitive liquid chromatography method for detecting phenolic antioxidants and parabens in commercial products. The technique offers a wide linear range for accurate quantification of these compounds.
Area of Science:
- Analytical Chemistry
- Food Chemistry
Background:
- Phenolic antioxidants and parabens are common additives in various commercial products.
- Accurate determination of these compounds is crucial for quality control and safety.
Purpose of the Study:
- To develop a rapid and sensitive method for quantifying phenolic antioxidants and parabens.
- To optimize liquid chromatography with amperometric detection for these analytes.
Main Methods:
- Liquid chromatography with amperometric detection (LC-AD).
- Direct injection of sample extracts onto a reverse-phase chromatography system.
- Analysis of phenolic antioxidants (e.g., BHA, TBHQ, propyl gallate, NDGA, Ionox-100) and parabens.
Main Results:
- The LC-AD method demonstrated high sensitivity and speed.
- A wide linear range from 10⁻¹¹ to 10⁻⁶ mole was achieved for analytes.
- Minimal interferences were observed in sample extracts.
Conclusions:
- Liquid chromatography with amperometric detection is a suitable technique for the determination of phenolic antioxidants and parabens.
- The method allows for efficient and reliable analysis in diverse commercial products.