Usefulness of chromatographic methods for the determination of drug-protein binding parameters

The reversible binding of anti-human serum albumin to poly beta-cyclodextrin-coated porous silica supports.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences·2006

[Pharmacology, an innovative factor in therapeutic research].

Annales pharmaceutiques francaises·2005

Evidence for resveratrol-induced preservation of brain mitochondria functions after hypoxia-reoxygenation.

Drugs under experimental and clinical research·2004

Dehydroepiandrosterone and alpha-estradiol limit the functional alterations of rat brain mitochondria submitted to different experimental stresses.

Neuroscience·2002

[In vitro protection of cerebral mitochondrial function by E-resveratrol in anoxia followed by re-oxygenation].

Bulletin de l'Academie nationale de medecine·2002

Binding of human serum albumin to silica particles by means of polymers: a liquid chromatographic study of the selectivity of resulting chiral stationary phases.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences·2002

Rapid synthesis of isoprenoid diphosphates and their isolation in one step using either thin layer or flash chromatography.

Journal of chromatography·2013

[Electrophoresis of radionuclides on cellogel].

Journal of chromatography·2012

Frontal affinity chromatography: theory for its application to studies on specific interactions of biomolecules.

Journal of chromatography·2010

Determination of the calcium antagonist SIM6080 in plasma by high-resolution gas chromatography.

Journal of chromatography·1994

Processing of envelope polypeptides of herpes simplex virus type 1. Demonstration of variation in different cell lines by high-performance liquid chromatography and radioimmunoprecipitation.

Journal of chromatography·1994

Measurement of GABA in rat brain microdialysates using o-phthaldialdehyde-sulphite derivatization and high-performance liquid chromatography with electrochemical detection.

Journal of chromatography·1994

Design, synthesis, and structure-activity relationships of ω-aryloxy-α-hydroxyalkanoates as selective lateral root inhibitors.

Organic & biomolecular chemistry·2026

A resource-efficient structure-based workflow for fragment progression enables parallel hit discovery and validation of functionally diverse modulators of NCS-1 protein-protein interactions.

Chemical science·2026

The role of natural products in the intestinal barrier: a bibliometric analysis from 2004 to 2025.

Frontiers in immunology·2026

Targeting a cryptic Magnaporthe oryzae-specific pocket in succinate dehydrogenase to combat rice blast.

Plant communications·2026

Cryo-EM structures of Candida albicans chitin synthase Chs1 reveal a druggable translocation channel.

Nature microbiology·2026

Targeting steroid receptors and aldo-keto reductases of 1C subfamily with bile acid derivatives: in vitro and in silico insights.

The Journal of steroid biochemistry and molecular biology·2026

Related Experiment Videos

Usefulness of chromatographic methods for the determination of drug-protein binding parameters

Related Concept Videos

The reversible binding of anti-human serum albumin to poly beta-cyclodextrin-coated porous silica supports.

[Pharmacology, an innovative factor in therapeutic research].

Evidence for resveratrol-induced preservation of brain mitochondria functions after hypoxia-reoxygenation.

Dehydroepiandrosterone and alpha-estradiol limit the functional alterations of rat brain mitochondria submitted to different experimental stresses.

[In vitro protection of cerebral mitochondrial function by E-resveratrol in anoxia followed by re-oxygenation].

Binding of human serum albumin to silica particles by means of polymers: a liquid chromatographic study of the selectivity of resulting chiral stationary phases.

Rapid synthesis of isoprenoid diphosphates and their isolation in one step using either thin layer or flash chromatography.

[Electrophoresis of radionuclides on cellogel].

Frontal affinity chromatography: theory for its application to studies on specific interactions of biomolecules.

Determination of the calcium antagonist SIM6080 in plasma by high-resolution gas chromatography.

Processing of envelope polypeptides of herpes simplex virus type 1. Demonstration of variation in different cell lines by high-performance liquid chromatography and radioimmunoprecipitation.

Measurement of GABA in rat brain microdialysates using o-phthaldialdehyde-sulphite derivatization and high-performance liquid chromatography with electrochemical detection.

Design, synthesis, and structure-activity relationships of ω-aryloxy-α-hydroxyalkanoates as selective lateral root inhibitors.

A resource-efficient structure-based workflow for fragment progression enables parallel hit discovery and validation of functionally diverse modulators of NCS-1 protein-protein interactions.

The role of natural products in the intestinal barrier: a bibliometric analysis from 2004 to 2025.

Targeting a cryptic Magnaporthe oryzae-specific pocket in succinate dehydrogenase to combat rice blast.

Cryo-EM structures of Candida albicans chitin synthase Chs1 reveal a druggable translocation channel.

Targeting steroid receptors and aldo-keto reductases of 1C subfamily with bile acid derivatives: in vitro and in silico insights.

Related Experiment Videos

Usefulness of chromatographic methods for the determination of drug-protein binding parameters

Related Concept Videos

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