Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

An OCT-reactivity classification to predict fetal outcome

C C Lin, A H Moawad, P River

    Obstetrics and Gynecology
    |July 1, 1980
    PubMed
    Summary

    The oxytocin challenge test (OCT) can predict fetal outcomes. A nonreactive OCT pattern indicates a compromised fetus, while a reactive pattern suggests good fetal health, improving prenatal diagnostics.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Preterm prediction study: comparison of the cervical score and Bishop score for prediction of spontaneous preterm delivery.

    Obstetrics and gynecology·2008
    Same author

    The preterm prediction study: can low-risk women destined for spontaneous preterm birth be identified?

    American journal of obstetrics and gynecology·2001
    Same author

    Occupational fatigue and preterm premature rupture of membranes. National Institute of Child Health and Human Development Maternal-Fetal Medicine, Units Network.

    American journal of obstetrics and gynecology·2001
    Same author

    Preterm delivery in women with pregestational diabetes mellitus or chronic hypertension relative to women with uncomplicated pregnancies. The National institute of Child health and Human Development Maternal- Fetal Medicine Units Network.

    American journal of obstetrics and gynecology·2000
    Same author

    Cervical length at 16-22 weeks' gestation and risk for preterm delivery.

    Obstetrics and gynecology·2000
    Same author

    The impact of digital cervical examination on expectantly managed preterm rupture of membranes.

    American journal of obstetrics and gynecology·2000

    Area of Science:

    • Obstetrics and Gynecology
    • Fetal Medicine
    • Perinatal Diagnostics

    Background:

    • The oxytocin challenge test (OCT) is used to assess fetal well-being.
    • Improving the predictive accuracy of the OCT for fetal outcomes is crucial for clinical decision-making.
    • Existing methods may not sufficiently differentiate between healthy and compromised fetuses.

    Purpose of the Study:

    • To propose an OCT-reactivity classification to enhance the prediction of fetal outcomes.
    • To evaluate the accuracy of this new classification in identifying fetuses at risk.
    • To correlate OCT patterns with specific maternal and fetal conditions.

    Main Methods:

    • Analysis of 293 cases undergoing the oxytocin challenge test (OCT).
    • Development and application of a novel OCT-reactivity classification system.

    Related Experiment Videos

  • Correlation of OCT patterns with perinatal outcomes, maternal conditions (pre-eclampsia-hypertension, IUGR), and biochemical markers (estriol levels).

    • Main Results:

    • All 6 perinatal deaths occurred in fetuses with a nonreactive OCT pattern.
    • A positive nonreactive test accurately predicted a 'sick' infant with 90% accuracy.
    • A negative reactive test reliably assured a good fetal outcome.
    • Nonreactive patterns were associated with pre-eclampsia-hypertension, intrauterine growth retardation (IUGR), low estriol levels, and suspected fetal compromise.
    • Positive OCT results correlated with IUGR, low estriol levels, and small placentas, indicating stressed fetoplacental reserves.

    Conclusions:

    • The proposed OCT-reactivity classification significantly improves the predictive value of the OCT for fetal outcome.
    • A nonreactive OCT pattern is a strong indicator of fetal compromise.
    • A reactive OCT pattern is associated with good fetal outcomes, reassuring clinicians.
    • The OCT is a valuable tool for assessing fetoplacental reserve under stress.