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[Pattern of steroid hormones in patients with acute leukemia]
Voprosy Onkologii
|January 1, 1980
Abstract:
The cortisol metabolism was studied in patients with different variants of acute leukemia. In total amount of C21-steroid excreted with urine the portion of cortisol was decreased, the increased cortisol conversion into 20-dihydrometabolites and the decreased cortisol portion, conversed through the stage of cortisone into tetrahydrocortisone, were observed. Also, disturbances in steroid conjugation with glucuronic and sulfuric acids and the increased progesterone concentration in peripheral blood plasma were noted.