Relationships between vasculogenesis and morphogenesis in the chick embryo spinal ganglia

By means of India ink injections in chicken embryos from the 3rd to the 14th incubation day, the development of the vascular pattern in the thoracic and lumbar spinal ganglia has been studied. A rather precise correlation has been observed between the successive steps in the formation of the endoganglionic vessel network and the ordered sequence of the proliferation and differentiation processes of the ganglionic neuroblasts: in fact, the developing vascular pattern seems to conform to the morphogenetic changes gradually undergone by the nervous substratum.