Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Localizing brain stem lesions with brain stem auditory evoked potentials

M Kjaer

    Acta Neurologica Scandinavica
    |May 1, 1980
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Tendon's 'first aid' response - new insights into acute tendon molecular reprogramming after rupture.

    The Journal of physiology·2025
    Same author

    Lower basal and postprandial muscle protein synthesis after 2 weeks single-leg immobilization in older men: No protective effect of anti-inflammatory medication.

    Physiological reports·2024
    Same author

    Acute loading has minor influence on human articular cartilage gene expression and glycosaminoglycan composition in late-stage knee osteoarthritis: a randomised controlled trial.

    Osteoarthritis and cartilage·2023
    Same author

    The regional turnover of cartilage collagen matrix in late-stage human knee osteoarthritis.

    Osteoarthritis and cartilage·2022
    Same author

    Effects of genipin crosslinking on mechanical cell-matrix interaction in 3D engineered tendon constructs.

    Journal of the mechanical behavior of biomedical materials·2021
    Same author

    Hoof conformation in Icelandic competition horses and its interrelationship with hoof pathologies and tölt performance.

    Veterinary journal (London, England : 1997)·2020
    Same journal

    Editorial.

    Acta neurologica Scandinavica·2022
    Same journal

    Advances in sudden unexpected death in epilepsy.

    Acta neurologica Scandinavica·2022
    Same journal

    Non-convulsive seizures and non-convulsive status epilepticus in neuro-intensive care unit.

    Acta neurologica Scandinavica·2022
    Same journal

    Positron emission tomography in autoimmune encephalitis: Clinical implications and future directions.

    Acta neurologica Scandinavica·2022
    Same journal

    Seizure detection based on wearable devices: A review of device, mechanism, and algorithm.

    Acta neurologica Scandinavica·2022
    Same journal

    Walking confidence and perceived locomotion ability explain participation after stroke: A cross-sectional experimental study.

    Acta neurologica Scandinavica·2022
    See all related articles

    Brain stem auditory evoked potentials (BAEPs) can detect clinically silent brain stem lesions, particularly in multiple sclerosis patients. However, BAEPs, like CT scans, struggle to precisely localize lesions to specific brain stem levels.

    Area of Science:

    • Neuroscience
    • Neurology
    • Audiology

    Background:

    • Brain stem auditory evoked potentials (BAEPs) are used to assess auditory pathway function.
    • Lesions within the brain stem can cause neurological deficits.
    • Previous studies suggested BAEPs could localize brain stem lesions.

    Purpose of the Study:

    • To evaluate the ability of BAEPs to localize brain stem lesions in patients with neurological disorders.
    • To compare BAEP findings with clinical assessment and CT scans for lesion localization.
    • To determine the utility of BAEPs in detecting clinically silent brain stem involvement.

    Main Methods:

    • A survey of BAEPs in animals and humans with localized brain stem lesions.
    • Clinical estimation of brain stem involvement in 155 neurological patients (multiple sclerosis, vascular disorders, etc.).

    Related Experiment Videos

  • Correlation of BAEP findings with clinical assessment and CT scan results.

    • Main Results:

    • BAEP examination showed potential for localizing lesions to high/low levels or diffusely within the brain stem.
    • Correlation between clinical and BAEP findings showed agreement for negative and diffuse abnormalities, but not for specific levels.
    • CT scanning also failed to consistently localize lesions to specific brain stem levels.
    • BAEPs were valuable in identifying clinically silent lesions, especially in multiple sclerosis patients with spinal signs.

    Conclusions:

    • BAEPs can detect brain stem lesions, including those not apparent clinically.
    • Precise localization of brain stem lesions to specific levels remains challenging with BAEPs and CT scans.
    • BAEPs are particularly useful for identifying subclinical brain stem involvement in diseases like multiple sclerosis.