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Relationship between pressure and digital vasculitis in rheumatoid disease
Annals of the Rheumatic Diseases
|April 1, 1980
Summary
This study found that pressure points causing skin blanching in rheumatoid arthritis patients often correspond to vasculitis lesions. This suggests vascular compression may contribute to rheumatoid vasculitis development.
Area of Science:
- Rheumatology
- Dermatology
- Vascular Biology
Background:
- Rheumatoid vasculitis is a serious complication of rheumatoid arthritis.
- The pathogenesis of rheumatoid vasculitis is not fully understood.
- Nailfold capillaroscopy is a common diagnostic tool for microvascular changes.
Purpose of the Study:
- To investigate the relationship between pressure-induced tissue blanching and the location of rheumatoid nailfold vasculitis lesions.
- To explore the potential role of vascular compression and stasis in rheumatoid vasculitis.
Main Methods:
- Comparison of 92 rheumatoid nailfold lesion sites with sites of tissue blanching during gripping.
- Visual assessment of blanching and lesion location.
Main Results:
- A significant correlation was observed between sites of tissue blanching and the presence of vasculitis.
- The findings indicate that pressure-induced blanching accurately predicts vasculitis locations.
Conclusions:
- Vascular compression and subsequent blood stasis are likely contributing factors in the development of rheumatoid vasculitis.
- This study provides insights into the mechanical factors influencing rheumatoid vasculitis.
- Further research into mechanical stress and vasculitis is warranted.