Pyoderma gangrenosum complicating non-Hodgkin's lymphoma

Area of Science:

• Dermatology
• Oncology
• Vascular Medicine

Background:

• Non-Hodgkin's lymphoma is a hematologic malignancy.
• Pyoderma gangrenosum is a rare, ulcerative inflammatory skin disease.

Observation:

• A patient with non-Hodgkin's lymphoma developed pyoderma gangrenosum.
• The skin lesion initiated at the site of dye injection for a lymphangiogram.

Findings:

• This case highlights a potential association between lymphangiography and pyoderma gangrenosum development in lymphoma patients.
• The inflammatory process may be triggered by the introduced dye or the procedure itself.

Implications:

• Further investigation is warranted to understand the pathomechanism linking lymphangiography and pyoderma gangrenosum in this context.
• Consideration of this association may inform diagnostic and treatment strategies for lymphoma patients presenting with skin ulcers.