[Change in the proliferative activity of hematopoietic stem cells following adrenalectomy]

An early decrease in the total cellularity and amount of bone marrow CFUs was recorded in (CBAxC57B)F1 adrenalectomized mice. This decrease was accompainied by a significant fall in the number of proliferating stem cells in the bone marrow and spleen, evaluated by the method of "thymidine suicide". After normalization of the total amount of CFUs followed by that of the bone marrow cellularity the level of cycling stem cells returned to initial.