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Abstract:
Clinicopathological features and follow-up of 150 cases of necrotizing enteritis observed over the period of 8 years at Miraj, India, are presented. This is a distinct pathological entity with seasonal occurrence, frequently affecting male patients of the low socioeconomic groups between the third and fifth decades of life. The symptoms are disproportionately greater than the physical signs. The ischaemic lesions, which mainly affect the jejunum, show a variable degree of severity ranging from segmental congestion and ulceration to extensive gangrene and perforation. In the early stage of the disease recovery is complete. Conservative treatment is preferred in early cases, surgery being indicated only for advanced lesions. No definite aetiology has been detected.
Insights
Necrotizing enteritis is a distinct condition affecting middle-aged men in lower socioeconomic groups. Early detection and conservative treatment lead to complete recovery, while advanced cases require surgery.
Area of Science:
- Gastroenterology
- Pathology
- Epidemiology
Background:
- Necrotizing enteritis is a serious intestinal condition.
- Understanding its clinicopathological features is crucial for effective management.
Purpose of the Study:
- To present the clinicopathological features and follow-up of 150 necrotizing enteritis cases.
- To analyze the seasonal occurrence and demographic distribution of the disease.
Main Methods:
- Retrospective analysis of 150 necrotizing enteritis cases over 8 years.
- Detailed review of patient demographics, clinical presentation, pathological findings, and treatment outcomes.
Main Results:
- The study identified necrotizing enteritis as a distinct entity with seasonal occurrence.
- Male patients aged 30-50 from lower socioeconomic groups were predominantly affected.
- Ischaemic lesions in the jejunum varied from congestion to gangrene and perforation.
- Early-stage disease showed complete recovery with conservative treatment; advanced lesions required surgery.
Conclusions:
- Necrotizing enteritis presents with disproportionately severe symptoms relative to physical signs.
- Early diagnosis and conservative management are key for favorable outcomes.
- Further research is needed to determine the definite aetiology of this condition.